A regression tree approach to identifying subgroups with differential treatment effects

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A regression tree approach to identifying subgroups with differential treatment effects.

In the fight against hard-to-treat diseases such as cancer, it is often difficult to discover new treatments that benefit all subjects. For regulatory agency approval, it is more practical to identify subgroups of subjects for whom the treatment has an enhanced effect. Regression trees are natural for this task because they partition the data space. We briefly review existing regression tree al...

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ژورنال

عنوان ژورنال: Statistics in Medicine

سال: 2015

ISSN: 0277-6715

DOI: 10.1002/sim.6454